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  • PT141 x 10
  • PT141 x 10

PT141 x 10


PubChem CID 9941379

Molecular Formula C50H68N14O10

    • Diamond LE, Earle DC, Rosen RC, Willett MS, Molinoff PB. Double-blind, placebo-controlled evaluation of the safety, pharmacokinetic properties and pharmacodynamic effects of intranasal PT-141, a melanocortin receptor agonist, in healthy males and patients with mild-to-moderate erectile dysfunction. Int J Impot Res. 2004 Feb;16(1):51-9. doi: 10.1038/sj.ijir.3901139. PMID: 14963471.

    • King SH, Mayorov AV, Balse-Srinivasan P, Hruby VJ, Vanderah TW, Wessells H. Melanocortin receptors, melanotropic peptides and penile erection. Curr Top Med Chem. 2007;7(11):1098-1106. PMID: 17584130; PMCID: PMC2694735.

    • Safarinejad MR, Hosseini SY. Salvage of sildenafil failures with bremelanotide: a randomized, double-blind, placebo controlled study. J Urol. 2008 Mar;179(3):1066-71. doi: 10.1016/j.juro.2007.10.063. Epub 2008 Jan 18. PMID: 18206919.

    These studies cover various aspects of PT141, including its safety, pharmacokinetic properties, and pharmacodynamic effects in healthy males and patients with mild-to-moderate erectile dysfunction, its effect on lower urinary tract symptoms in men with erectile dysfunction, its use in treating erectile dysfunction in men taking dual antidepressants, its role in treating hypoactive sexual desire disorder, and its ability to induce erections in men with psychogenic erectile dysfunction.

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